SHIKONIN CAS 517-89-5 Shikonine

CAS:517-89-5

synonyma:

5,8-Dihydroxy-2-[(R)-1-hydroxy-4-methyl-3-pentenyl]-1,4-naphthalenedione; TokyoViolet; (R)-5,8-Dihydroxy-2-(1-hydroxy-4-Methylpent-3-en-1-yl)naphthalen-1,4-dione; SHIKONIN(AS); Shikonin, ex MArnebiasp.; (-)-Shikonin Sinarum; Shikonine; Shikonin. 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalen-1,4-dione.

Nomen Marcae: Unilong
Locus Originis: Shandong, Sina
Puritas: 99%

Nomen producti: SHIKONIN

Sarcina: 25kg/tympanum

Traditio: Statim

MF:C16H16O5

MW:288.3

Nuntium Tuum Relinque

Detalia Producti

Deprime

Etiquettae Productarum

Quid estSHIKONIN

Crystallum aciculare purpureo-brunneum, punctum liquefactionis 147°C, rotatio optica αD20 = +135° (benzenum). Solubile in aethere phenethylico, acetono, chloroformio, methanolo, aethanolo, glycerolo, oleis animalibus et vegetabilibus et solutionibus aquosis alcalinis, insolubile in aqua. Color mutatur cum valore pH, rubro pH 4-6, purpureo pH 8, caeruleo pH 10-12. Bona resistentia luci, calori et oxidationi, instabilis dosi reducenti, et purpureo obscuro in casu ionum ferri. Effectum antibacterialem quendam habet.

SpecificatioSHIKONIN

CAS	517-89-5
Alia Nomina	Shikonine
Aspectus	pulvis purpureus
Puritas	99%
Color	purpureus
Repositorium	Refrigerata et Siccata Conservatio
Sarcina	25kg/sacculus
Applicatio	Cibus

ApplicatioSHIKONIN

(1) Effectus hypoglycaemicus Extractum foliorum Consolidae et polysaccharidum (A, B, C) Consolidae effectum hypoglycaemicum manifestum habent.

(2) Effectus bacteriostaticus: Lithospermum in vitro effectum inhibitorium in virus Jingke 68-1 et in Staphylococcus aureus habet. Effectus levoshikonini contra virus parainfluenzae per reactionem haemagglutinationis et methodum cytopathicam investigatus est. Resultata demonstraverunt lithospermum toxicitatem humilem intra ambitum concentrationis in experimento adhibitum habere, et certam actionem in vitro contra virus influenzae necandi virus parainfluenzae.

(3) Effectus in coagulationem sanguinis: Iniectio intraperitonealis componentium shikonini (shikonin, acetylshikonin) tempus coagulationis sanguinis non afficit, sed effectum anticoagulantem heparini impedire potest.

(4) Effectus antitumoralis Extractum consolidae quendam effectum inhibitorium in stadio posteriore (phasi G2) synthesis DNA in cellulis Hela habet.

(5) Effectus antitumoralis Shikonin proliferationem inhibet, apoptosis promovet et cessationem cycli cellularis in cultis stirpibus cellularum choriocarcinomatis humani medicamentis resistentium (JAR/MTX) in vitro inducit. Experimenta ostendunt concentrationem shikonini cum dosi crescere. Et prolongatione temporis actionis, rata inhibitionis crescentiae cellularum choriocarcinomatis medicamentis resistentium etiam significanter aucta est.

(6) Effectus in secretionem hormonum Effectus shikonini in functionem axis hypothalamo-pituitarii-gonadalis in muribus feminis adolescentibus demonstravit gradus hormonum sericos in grege shikonini significanter inferiores fuisse quam in grege negativo comparationis, et nullam differentiam significantem comparatione cum grege positivo comparatione factam esse. Demonstratur shikonin functionem axis hypothalamo-pituitarii-gonadalis in muribus inhibere posse.

(7) Effectus antioxidantis Nonnulli investigatores facultatem shikonini ad radicalem superoxidi (O2-) et radicalem 1,1-diphenyl-2-picrophenhydrazin (DPPH) tollendam mensuraverunt, necnon effectum eius in inhibitionem systematis autooxidationis caroteni/acidi linoleici β-. Resultata demonstraverunt shikoninum facultatem validam ad DPPH et O2- tollendum habere, et effectum inhibitorium manifestum in systema autooxidationis β-caroteni/acidi linoleici habuisse. Magna capacitas antioxidantis.