SHIKONIN CAS 517-89-5 Shikonine

CAS:517-89-5

synonyms

5,8-dihydroxy-2-[(R)-1-hydroxy-4-methyl-3-penteryl] 1,4-naphthalenedione;TokyoViolet;(R)-5,8-dihydroxy-2-(1-hydroxy -4-Methylpent-3-en-1-yl)naphthalene-1,4Chemicalbook-dione;SHIKONIN(AS);Shikonin,froMArnebiasp.;(-)-ShikoninChina; ) -1-hydroxy-4-methyl-pent 3-enyl]naphthalene-1,4-dione

Nomen notam: Unilong
Locus Origin: Shandong, China
Puritas: 99%

Product nomen: Shikonin

Packing:25kgs/drum

Partus: Statim

MF:C16H16O5

MW:288.3

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Quid est?SHIKOIN

Acus purpureus cristallus, punctum liquescens 147℃, rotatio optica αD20=+35°(benzene). Solubilia in aethere phenethyl, acetono, chloroformi, methanolo, ethanolo, glycerolo, oleis animalis et vegetabilibus et solutionibus alcalini aqueis, in aqua solubilibus. Color cum Ph valore mutat, cum Ph valoris 4—6 rubentis, Ph valor 8 esse purpureus, Ph valor 10—12 caeruleus. Bonum lucis resistentia, resistentia caloris et resistentia oxidationis, instabilis ad reducendum dosis, et purpurea in ferro iones obscura. Antibacteria quemdam effectum habet.

Specification ofSHIKOIN

CAS	517-89-5
Alia Nomina	Shikonine
Aspectus	purpura pulveris
Puritas	99%
Color	purpura
Repono	Refrigescant Aridae PRAECLUSIO
sarcina	25kg/bag
Applicationem	Cibus

Applicationem of *SHIKOIN

(1) Hypoglycemicus effectus Folium extractum comfrey et polysaccharidis (A, B, C) comfrey effectum hypoglycemicum conspicuum habent.

(2) Bacteriostatic effectus Lithospermi effectum inhibitorium in Jingke 68-1 virum in vitro habet, et effectum inhibitorium in Staphylococcus aureus habet. Virus anti-parainfluenza effectus levoshikonin studuit per reactionem hemagglutinationis et methodi cytopathicae. Eventus ostendit se in low toxicitatem habere in usu extensionis in experimento et certas habuisse in vitro anti-influenza virus activitatem et directam occisionem viri parainfluenzae. effectum.

(3) Effectus sanguinis coagulationis: iniectio intraperitonealis partium shikonin (shikonin, acetylshikonin) non afficit tempus sanguinis coagulationis, sed impedire potest effectum anticoagulantis heparin.

(4) Anti-tumor effectus Comfrey extractum quendam inhibendi effectum habet in scaena nuper (G2 phase) synthesis DNA in cellulis Hela.

(5) Antitumor effectus Shikonin multiplicationem vetat, apoptosin promovet et cyclum cellularum inducit in cultura humana choriocarcinoma medicamento-resistentes lineae cellae (JAR/MTX) in vitro. Experimenta ostendunt concentrationem shikonin cum dose augere. Et prolongatio temporis actionis, inhibitio rate incrementi choriocarcinomatis pharmaci-repugnantis cellulis signanter augetur.

(6) Effectus secretionis hormonum Effectus shikonin in functione axis hypothalamico-pituitarii-gonadalis in adolescente muliebre mures ostenderunt serum hormonum gradus in shikonin globi signanter inferiores esse quam coetus in potestate negativa, et facta est. nulla differentia magna cum positivo potestate coetus. diuersa. Ostendit shikonin inhibere munus axis hypothalamico-pituitarii-gonadalis in muribus.

(7) Antioxidant effectus Nonnulli investigatores scaventing facultatem shikonin mensuraverunt ad superoxidum radicale (O2-) et 1,1-diphenyl-2-picrophenhydrazinum radicale (DPPH), eiusque effectum ab β- - Inhibitione acidi caroten/linoleici autoxidationis. ratio. Eventus ostendit shikonin magnam scavendendi facultatem ad DPPH et O2- habuisse, et effectum inhibitorium manifestum habuisse in systemate auto-oxidationis acidi β-caroten/linoleici. Facilisis magna validus.